About one or two decades ago, people saw biology and computer science as two entirely different fields. Bioinformatics is the use of information technology in biotechnology for the data storage, data warehousing and analyzing the DNA sequences. If you continue browsing the site, you agree to the use of cookies on this website. 2. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. It covers emerging scientific research and the exploration of proteomes from the overall level of intracellular protein composition (protein profiles), protein structure… If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein. The main areas of genetic research include; genetic testing, reproductive genomics, gene therapy, genomic databanks and pharmacogenomics all of which influence the management of disease at different stages. Many of the children born in this demographic die soon after birth because of the devastating effects of their condition. Clipping is a handy way to collect important slides you want to go back to later. Upcoming SlideShare. Genetic research is continually becoming important in the transformation of healthcare as its role in the diagnosis and treatment of various conditions can never be overemphasized. An additional role for bioinformatics in genome-based therapies is to collect information on all of the human genes and proteins. Looks like you’ve clipped this slide to already. View. The advent of function-based gene discovery by systems such as full-length cDNA overexpressor (FOX) gene hunting, which use full-length cDNA transgenic plants as overexpressors, has provided an effective approach to high-throughput discovery of functional genes associated with phenotypic changes (Ichikawa et al. .uni-rostock.deDNA makes RNA makes Protein:Expression data• More copies of mRNA for a gene leads to more protein• mRNA can now be measured for all the genes in a cell at ones through microarray technology• Can have 60,000 spots (genes) on a single gene chip• Color change gives intensity of gene expression (over- or under-expression) Ulf Schmitz, Introduction to genomics and … Gene therapy of the middle ear is feasible with a FIV-based vector. Learn about approaches to and issues surrounding gene therapy. Bioinformatics has become a buzzword in today’s world of Science. You can change your ad preferences anytime. See our User Agreement and Privacy Policy. Not only to develop algorithms, store, retrieve, organize and analyze biological data but to CURATE data 3 Bioinformatics develops algorithms and biological software of computer to analyze and record the data related to biology for example the data of genes, proteins, drug ingredients and metabolic pathways. 2009). You can change your ad preferences anytime. 1. Bioinformatics has not only become essential for basic genomic and molecular biology research, but is having a major impact on many areas of biotechnology and biomedical sciences. The era of Genomic Revolution resulted in the generation of a large amount of genomic data, a new development that caused an urgent need for an integrated system to manage the huge amount of data. Bioinformatics Applications in Biotechnology 2. 1) Protein sequence can be determined by DNA sequencing. 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